Pulmonary toxicity following bleomycin use: A single-center experience

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Pulmonary toxicity of bleomycin.

Diffuse pulmonary fibrosis is associated with bleomycin administration to humans. The sequential reactions of lung cells to this drug have now been investigated in mice following injection of 20 mg/kg bleomycin twice per week for 4 to 8 weeks. Cytoplasmic and subendothelial edema was first observed in large vessels and by 4 weeks involved the capillaries. The reaction in many animals did not pr...

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ژورنال

عنوان ژورنال: Journal of Cancer Research and Therapeutics

سال: 2017

ISSN: 0973-1482

DOI: 10.4103/0973-1482.204887